Intestinal and renal handling of oxalate loads in normal individuals and stone formers
نویسندگان
چکیده
منابع مشابه
Two-carbon oxalogenesis compared in recurrent calcium oxalate stone formers and normal subjects.
We used a xylitol load to test the two-carbon pathway to oxalate production in humans. Use of this pentose sugar caused a fourfold increase in glycolate excretion, indicating its suitability as a dynamic function test of two-carbon metabolism. However, despite this increase in glycolate excretion in 10 recurrent stone formers and six normal subjects, there was no concomitant increase in oxalate...
متن کاملRenal and intestinal handling of oxalate following oxalate loading in rats.
BACKGROUND The enteric excretion of oxalate has been established in rats with chronic renal failure induced by 5/6 nephrectomy [Hatch et al.: Regulatory aspects of oxalate secretion in enteric oxalate elimination. JASN 1999;10:S324] and this response is mediated by angiotensin II receptor activation. However, the renal and intestinal handling of oxalate has not been evaluated for other common m...
متن کاملPercutaneous renal biopsy specimens in stone formers.
A series of renal biopsy specimens taken at the time of percutaneous nephrolithotomy were investigated for the presence and location of foci of microcalcification. Calcium was found in 18 of 25 (72%) of biopsy specimens from stone formers and in only seven of 30 (23%) of control biopsy specimens. This may indicate defective intrarenal handling of calcium as plasma calcium concentration was norm...
متن کاملThe diurnal variation in urine acidification differs between normal individuals and uric acid stone formers
Many biological functions follow circadian rhythms driven by internal and external cues that synchronize and coordinate organ physiology to diurnal changes in the environment and behavior. Urinary acid-base parameters follow diurnal patterns and it is thought these changes are due to periodic surges in gastric acid secretion. Abnormal urine pH is a risk factor for specific types of nephrolithia...
متن کاملChanges in urinary nanocrystallites in calcium oxalate stone formers before and after potassium citrate intake
The property changes of urinary nanocrystallites in 13 patients with calcium oxalate (CaOx) stones were studied before and after ingestion of potassium citrate (K3cit), a therapeutic drug for stones. The analytical techniques included nanoparticle size analysis, transmission electron microscopy, X-ray diffraction, and Fourier-transform infrared spectroscopy. The studied properties included the ...
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ژورنال
عنوان ژورنال: Urological Research
سال: 2007
ISSN: 0300-5623,1434-0879
DOI: 10.1007/s00240-007-0090-8